Understanding the origin of the remarkable efficiency of distant galaxy formation
The James Webb Space Telescope is revolutionizing our understanding of the distant universe. A result has emerged that challenges our models: the extremely high efficiency of star formation in distant galaxies. However, this finding is derived indirectly: we measure the mass of stars in galaxies, not their star formation rate. This is the main weakness of the James Webb. The aim of this thesis is to remedy this weakness by using its angular resolution capacity, which has not been taken into account until now, in order to obtain a more robust measurement of the SFR of distant galaxies. We will deduce a law that will improve the robustness of SFR determination using morphological properties and combining data from the James Webb Space Telescope with data from ALMA (z=1-3). We will then apply it to the distant universe (z=3-6, part 2) and use it as a benchmark for numerical simulations (part 3).
Aurorae are well known optical phenomena in the Solar System planets. Aurorae have great diagnostic value, as their emissions reveal the planets’ atmospheric compositions, the occurrence of magnetic fields and the solar wind conditions at the planet’s orbit. Looking for aurorae on exoplanets and brown dwarfs is the next frontier. A first breakthrough in this direction has occurred recently, with the detection of a CH4 emission attributed to auroral excitation on the brown dwarf W1935. This detection, and the prospects of observing other auroral features with existent and upcoming telescopes, is what motivates this project. In particular, we will build the first model dedicated to investigate CH4 and H3+ auroral emission on exoplanets and brown dwarfs. The model will be used to investigate the conditions at W1935, and to predict the detectability of aurorae on other sub-stellar objects.
Understanding and modulating resistance to transferrin receptor targeted internal radiotherapy.
This project aims to unravel the mechanisms of resistance to transferrin receptor–targeted internal radiotherapy (RIV-Tf) in lung cancer. RIV-Tf may combine localized cytotoxic effects with a potential modulation of the tumor microenvironment, offering a promising thera(g)nostic strategy. Preliminary data show significant tumor reduction without complete remission, suggesting adaptive resistance mechanisms. The project integrates transcriptomic analyses enabled by a microfluidic platform developed at LICB and various biological techniques (flow cytometry, ELISA, western blot, targeted imaging) to identify molecular and immunological signatures associated with treatment response. These signatures will be validated in vivo to guide rational therapeutic combinations. Conducted jointly by the ImmunoMaps and LICB teams at CEA, this multidisciplinary work will deepen our understanding of the interplay between radiobiology and tumor immunity and help optimize RIV efficacy in oncology.
Exploring trends in rocky exoplanets observed with JWST
One of JWST’s major goals is to characterize, for the first time, the atmospheres of rocky, temperate exoplanets, a key milestone in the search for potentially habitable worlds. The temperate rocky exoplanets accessible to JWST are primarily those orbiting M-type stars. However, a major question remains regarding the ability of planets orbiting M-dwarfs to retain their atmospheres.
In 2024, an exceptional 500-hour Director’s Discretionary Time (DDT) program, entitled Rocky Worlds, was dedicated to this topic, underlining its strategic importance at the highest level (NASA, STScI).
The main objective of this PhD project is to: 1) Analyze all available JWST/MIRI eclipse data for rocky exoplanets from Rocky Worlds and other public programs using a consistent and homogeneous framework; 2)Search for population-level trends in the observations and interpret them using 3D atmospheric simulations.
Through this work, we aim to identify the physical processes that control the presence and composition of atmospheres on temperate rocky exoplanets.
Spatiotemporal shaping of high-order harmonic emission in nanostructured crystals
We propose to study the spatiotemporal manipulation of radiation emitted by high harmonic generation, leveraging advances in nanofabrication technologies. The approach involves transposing methods developed for meta-optics to the strong-field regime specific to harmonic generation. The candidate will explore various design strategies to control the spatiotemporal properties of this radiation, which is intrinsically linked to the broad spectral bandwidth of attosecond pulses. These concepts will then be implemented and experimentally validated. This project aims to enhance the integration of high harmonic generation into optoelectronic devices, paving the way for new applications in ultrafast photonics.
New concepts for cold neutron reflectors
The CEA and the CNRS have launched an initiative to design a new neutron source using low-energy proton accelerators, the ICONE project [1]. The goal is to build a facility that will provide an instrumental suite of about ten spectrometers available to the French and European scientific community. Alongside ICONE, the LLB is also participating in HiCANS R&D work on the construction of a platform in Bilbao to facilitate European collaborations.Neutron scattering experiments require thermal and cold neutrons. The design of the moderator is therefore a crucial component of the project to maximize the source's performance.
One avenue for improving the moderator performances is to enhance the efficiency of the reflector, and more specifically, the cold neutron reflector. In this study, we propose to investigate the specific scattering properties of cold neutrons on nanostructured materials. Indeed, cold neutrons have long wavelengths (> 0.4 nm) and can therefore be coherently scattered by nanostructured materials. Scattering efficiency is not only amplified by coherent scattering effects, but it is potentially possible to direct this scattering if the reflecting material is anisotropic. This control over the scattering direction can further increase the moderator's brightness.
The first part of the work will consist of identifying the most promising nanostructured materials and modeling their cold neutron reflectivity performance. In a second step, these materials will be shaped and their properties characterized using neutron scattering devices at neutron scattering facilities such as the ILL in Grenoble or the PSI in Switzerland.
CONTEXT: strain - texture neutron instrumentation for ICONE
The CEA and the CNRS have launched an initiative to design a new neutron source using low-energy proton accelerators, the ICONE project. The objective is to build a facility that will offer an instrumental suite of about ten spectrometers available to the French and European scientific community. The project is currently in the Preliminary Design phase, with the aim of refining as much as possible all technical aspects.
We are proposing a PhD thesis on the modeling and development of a new neutron scattering spectrometer for measuring textures and stresses in materials. This technique makes it possible to probe residual stresses in materials after machining, heat treatment, and/or use, and to measure the crystallographic anisotropy of alloys to exploit the induced mechanical properties.
Part of the work will take advantage of the start-up of the DREAM and MAGIC spectrometers at ESS in Sweden, in which the LLB participated in the construction, so that the candidate can become familiar with time-of-flight neutron scattering techniques (measurements and data analysis).
In the second part of this work, we propose to implement statistical modulation techniques for the construction of an instrument, CONTEXT, on ICONE, which will allow to best exploit the potential of ICONE's long pulses. The objective will be to create a digital twin of the future instrument using various Monte Carlo simulation tools.
Attosecond photoemission spectroscopy of molecular gases and liquids
The aim of the thesis is to perform attosecond photoemission spectroscopy on molecules in the gas and liquid phase exploiting a novel high repetition rate Ytterbium laser system. These studies will unveil the processes of photoionization of inner/outer shells and the dynamics of electron scattering in real time.
Magnetic Tunnel Junctions at Boundaries
Spin electronics, thanks to the additional degree of freedom provided by electron spin, enables the deployment of a rich physics of magnetism on a small scale, but also provides breakthrough technological solutions in the field of microelectronics (storage, memory, logic, etc.) as well as for magnetic field measurement.
In the field of life sciences and health, giant magnetoresistance (GMR) devices have demonstrated the possibility of measuring the very weak fields produced by excitable cells on a local scale (Caruso et al, Neuron 2017, Klein et al, Journal of Neurophysiology 2025).
Measuring the information contained in the magnetic component associated with neural currents (or magnetophysiology) can, in principle, provide a description of the dynamic, directional and differentiating neural landscape. It could pave the way for new types of implants, thanks to their immunity to gliosis and their longevity.
The current bottleneck is the very small amplitude of the signal produced (<1nT), which requires averaging the signal in order to detect it.
Tunnel magnetoresistances (TMR), in which a spin-polarised tunnel current is measured, offer sensitivity performance that is more than an order of magnitude higher than GMR. However, they currently have too high a level of low-frequency noise to be fully beneficial, particularly in the context of measuring biological signals.
The aim of this thesis is to push back the current limits of TMRs by reducing low-frequency noise, positioning them as break sensors for measuring very weak signals and exploiting their potential as amplifiers for small signals.
To achieve this objective, an initial approach based on exploring the materials composing the tunnel junction, in particular those of the so-called free magnetic layer, or on improving the crystallinity of the tunnel barrier, will be deployed. A second approach, consisting of studying the intrinsic properties of low-frequency noise, particularly in previously unexplored limits, at very low temperatures where intrinsic mechanisms are reached, will guide the most promising solutions.
Finally, the most advanced structures and approaches at the state of the art thus obtained will be integrated into devices that will provide the building blocks for going beyond the state of the art and offering new possibilities for spin electronics applications. These elements will also be integrated into systems for 2D (or even 3D) mapping of the activity of a global biological system (neural network) and for evaluating capabilities for clinical cases (such as epilepsy or motor rehabilitation).
It should be noted that these improved TMRs may have other applications in the fields of physical instrumentation, non-destructive testing, and magnetic imaging.
Numerical Study of Interstellar Turbulence in the Exascale Era
This PhD project aims to better understand interstellar medium turbulence, a key phenomenon governing the formation of stars and galactic structures. This turbulence—magnetized, supersonic, and multiphase—influences how energy is transferred and dissipated, thereby regulating the efficiency of star formation throughout the history of the Universe. Its study is complex, as it involves a wide range of spatial and temporal scales that are difficult to reproduce numerically. Advances in high-performance computing, particularly the advent of GPU-based exascale supercomputers, now make it possible to perform much more refined simulations.
The Dyablo code, developed at IRFU, will be used to carry out large-scale three-dimensional simulations with adaptive mesh refinement to resolve the regions where energy dissipation occurs. The study will progress in stages: first, simulations of simple isothermal flows will be conducted, followed by models that include heating, cooling, magnetic fields, and gravity. The turbulent properties will be analyzed using power spectra, structure functions, and density distributions, in order to better understand the formation of dense regions that give birth to stars. Finally, the work will be extended to the galactic scale, in collaboration with other French institutes, to investigate the large-scale energy cascade of turbulence across entire galaxies.