Development of microfluidic photoreactors for reproducible, quantitative evaluation of photoactive materials, coupled with on-line analysis by mass spectrometry and gas chromatography

The development of high performance photoactive materials (catalysts, semiconductors, sensitive films) for chemical conversion under light irradiation requires precise, reproducible and quantitative evaluation methods. Conventional batch approaches suffer from major limitations: poor control over residence time, temperature or light gradients, low exposed specific surface area and variable reproducibility. In this context, microfluidic photoreactors offer a promising alternative for structured screening and fine evaluation of photoactive materials, in particular thanks to their high surface/volume ratio, flow control and geometry adaptable to different irradiation configurations.
This work, linked to the PEPR LUMA SUNRISE project, aims to design, fabricate and characterize photonic microreactors specifically adapted to the fine evaluation of photoactive materials. The aim is to create a platform capable of generating quantitative and comparable data on the performance and stability of these materials, under well-defined conditions of throughput, irradiation and reaction environment, and then to couple them to high-level analytical techniques (GC, MS) for on-line identification of the products generated.
We propose to develop 4 axes during this thesis project: 1) development, characterization and optimization of the microfluidic platform for online liquid and gas measurement; 2) implementation of protocols for the deposition of photoactive materials 3) evaluation of photochemical performance and validation of the system with samples provided (SUNRISE partners) and on the degradation of pollutant by photochemistry (collaboration with a thesis in progress at the laboratory) and 4) Coupling of the reactor to online analytical methods (GC, MS).

Fine-grained and spatio-temporally grounded large multimodal models

This PhD project focuses on enhancing Large Multimodal Models (LMMs) through the integration of fine-grained and spatio-temporal information into training datasets. While current LMMs such as CLIP and Flamingo show strong performance, they rely on noisy and coarse-grained image-text pairs and often lack spatial or temporal grounding. The thesis aims to develop automatic pipelines to enrich image datasets with geographic and temporal metadata, refine captions using fine-grained semantic descriptors, and balance dataset diversity and compactness by controlling class-wise sample sizes.

Training strategies will incorporate hierarchical class structures and adapt protocols to improve alignment between caption elements and image regions. The work will also explore joint training regimes that integrate fine-grained, spatial, and temporal dimensions, and propose set-based inference to improve the diversity of generated outputs. The enriched datasets and models will be evaluated using existing or newly developed benchmarks targeting contextual relevance and output diversity. The project also addresses challenges in metadata accuracy, efficient model adaptation, and benchmarking methodologies for multi-dimensional model evaluation.

Applications include improved synthetic data generation for autonomous driving, enhanced annotation of media archives through contextual captioning, and better visual reasoning in industrial simulation scenarios.

In-depth electrical and material characterization of low-K spacer

As part of the European Chip Act, CEA-Leti is pioneering a new generation of transistors using FDSOI architecture. Our goal is to deliver advanced performance with a strong emphasis on materials and energy efficiency. As we push the limits of planar transistors at 10 nm and 7 nm, we face significant physical challenges, particularly in reducing parasitic elements like capacitance and access resistance, which are critical for minimizing energy loss and optimizing performance. We are eager to tackle these challenges together.
We are excited to offer a unique PhD opportunity for motivated students interested in the field of semiconductor device engineering. Join our team to work on the incorporation and characterization of low-k spacer for advanced 7-10nm FDSOI Technology. This PhD offers the chance to work on a groundbreaking project. If you're curious, innovative, and eager for a challenge, this opportunity is perfect for you!
The impact of the dielectric spacer nature has relevant effects on the overall transistor performances, specifically in non-fully overlapped configuration. The dielectric spacer integration, optimization and engineering remains a challenge and becomes crucial to address technology advancement and scaling down demand. Numerous spacer candidates (SiN, SiCO, SiCON, SiCBN) have been introduced and identified as promising solutions, however, they frequently suffer from inherent defects and adverse electrical characteristics, such as charge trapping and presence of undesired interface states, which hinder their and the overall transistors performance.
Within this framework, the objective of this PhD is to conduct a comprehensive investigation and electrical characterization (CV,IV, BTI, HCI…) of the material spacer (interface, volume), providing an in-depth analysis of transistor performance and its underlying mechanisms. Innovative ultrafast CV stress-measurement characterization on dielectric samples will be also carried out and the correlation between trapping performance and the deposition parameters used in their fabrication will be established. Additionally, the candidate will collaborate closely with experts to contribute to the thin film deposition and characterization of new materials through surface analyses and thin-film characterizations (ellipsometry, FTIR, XRR, XPS…)
Throughout this journey, you will gain a broad spectrum of knowledge, spanning microelectronics materials and processes, analog integrated design, all while addressing the unique challenge of advance 7-10 nm FDSOI technology. You'll collaborate with multidisciplinary teams to develop a deep understanding of FDSOI devices and analyze existing and new measurements. You'll also be part of an integrated multidisciplinary lab, working alongside a team composed of several permanent researchers, exploring a wide range of research applications.

Simplified Model for Rotary Tube Calcination

Since the vitrification lines at La Hague began operation in 1989, ORANO (formerly AREVA) has faced difficulties in controlling the calciner. Actions taken to significantly reduce these problems have considerably eased them, but without completely eliminating them. Most of the recommended actions are based on expert opinions, which themselves are based on inactive test results that don't cover all situations encountered by ORANO. To definitively resolve these control difficulties, it was decided to launch a more theoretical modeling study, while simultaneously investigating new calciner control instrumentation.

Microfluidics for biomimetic detection of airbone pathogens

Air represents a complex contamination pathway that is difficult to control and through which numerous biological, biochemical, or chemical agents can affect populations and healthcare workers. Standard detection approaches, whether qPCR, antigen tests, or ELISA tests, rely on reagents specific to known and targeted agents. These approaches are therefore unsuitable for detecting an unknown pathogen that could result in a new pandemic. To face such unknown agents, new biosensors will be needed to distinguish between pathogenic and non-pathogenic agents. Also, these sensors will have to be miniature for deployment.

With a new microfluidic system the present project aims to explore original approaches for conducting such detection without preconceived notions. Based on the laboratory's experience and developments, the PhD will include :
- developing new materials and designs to optimize and to enable multiple bioaerosol sampling;
- developing a biomimetic biochip and optimize molecular interactions using microflows controlled at the micro/milliscale.

You will design a microfluidic card integrating new detection strategies and study them experimentally using prototypes already developed in the laboratory.

Optimization of transports in the Gas Diffusion Layers of Proton Exchange Membrane Fuel Cells: Artificial Intelligent as a support to define optimal porous structures and usage

The design and manufacturing of innovative materials with required properties is a key objective for developing advanced technologies in the field of energy, such as Hydrogen and Alcaline fuel cells and Electrolysers. These improvements will contribute to propose even more attractive low-carbon electrical energy systems, with reduced pollution and green-house effects.
This thesis focuses on the Gas Diffusion Layer (GDL) which plays a crucial role on the performance and durability of Proton Exchange Membrane Fuel Cell (PEMFC).
Your main aim will be to set-up a numerical approach so as to propose improved porous structures to optimize the different transports inside a GDL, for given targets and constraints. To do so, you will make the bridge between advanced modeling of (electrical, heat, liquid, gas) transports in 3D porous media and artificial intelligence. You will then analyze the influence of the operating conditions on such optimal structures and propose design recommendations.
This work will be conducted in close relationship between world-renowned scientific actors : the fuel cells and the modelling teams of CEA/LITEN (Grenoble), the specialists of transports in porous media at CNRS/IMFT (Toulouse), and the specialists of GDL, modeling and AI at FZJ (Juelich, https://www.fz-juelich.de/en).
Scientific publications are expected and patents could also be proposed.

Machine Learning-Accelerated Electron Density Calculations

Density Functional Theory (DFT) in the Kohn-Sham formalism is one of the most widespread methods for simulating microscopic properties in solid-state physics and chemistry. Its main advantage lies in its ability to strike a favorable balance between accuracy and computational cost. The continuous evolution of increasingly efficient numerical techniques has constantly broadened the scope of its applicability.
Among these techniques that can be associated with DFT, machine learning is being used more and more. Today, a very common application consists in producing potentials capable of predicting interactions between atoms using supervised learning models, relying on properties computed by DFT.
The objective of the project proposed as part of this thesis is to use machine learning techniques at a deeper level, notably to predict the electronic density in crystals or molecules. Compared to predicting properties such as forces between atoms, calculating the electronic density presents certain challenges: the electronic density is high-dimensional since it must be calculated throughout all space; its characteristics vary strongly from one material to another (metals, insulators, charge transfer, etc.). Ultimately, this can represent a significant computational cost. There are several options to reduce the dimensionality of the electronic density, such as computing projections or using localization functions.
The final goal of this project is to be able to predict, with the highest possible accuracy, the electronic density, in order to use it as a prediction or as a starting point for calculations of electron-specific properties (magnetism, band structure, for example).
In a first stage, the candidate will be able to implement methods recently proposed in the literature; in a second part of the thesis, it will then be necessary to propose new ideas. Finally, the implemented method will be used to accelerate the prediction of properties of large systems involving charge transfers, such as defect migration in crystals.

Automatic modelling language variations for socially responsive chatbots

Conversational agents are increasingly present in our daily lives thanks to advances in natural language processing and artificial intelligence and are attracting growing interest. However, their ability to understand human communication in all its complexity remains a major challenge. This PhD project aims to model linguistic variation to develop agents capable of socially adaptive interactions, taking into account the socio-demographic profile and emotional state of their interlocutors. It also focuses on evaluating linguistic cues at different levels, leveraging both spoken and written language varieties, and assessing the generalization capacity of models trained on multilingual and multi-situational data, with the goal of improving interaction modeling with conversational agents.

Compositional Generalization of Visual Language Models

The advent of the foundation models led to increase the state-of-the art performance on a large number of tasks in several fields of AI, in particular computer vision and natural language processing. However, despite the huge amount of data used to train them, these models are still limited in their ability to generalize, in particular for a use case of interest that is in a specific domain, not well represented on the Web. A way to formalize this issue is compositional generalization, i.e. generalising to a new, unseen concept from concepts learned during training. This "generalization" is the ability to learn disentangle concepts and to be able to recombine
them into unseen composition when the model is in production. The proposed thesis will address this issue, aiming at proposing visual representations that enable generic visual language models to generalize compositionally within specific domains. It will investigate strategies to reduce shortcut learning, promoting deeper understanding of compositional structures in multimodal data. It will also address the problem of compositional generalization beyond simple attribute–object pairs, capturing more subtle and complex semantics. The proposed thesis aims at proposing preogress at a quite theoretical level but has many potential practical interest, in the fields of health, administration and services sectors, security and defense, manufacturing and agriculture.

Towards real-time simulation of thermal scenes in a tokamak to support plasma operations.

Monitoring the surface temperatures and heat fluxes of the walls in nuclear fusion devices is crucial for the operation of fusion machines. To ensure the reliability of these measurements, particularly through infrared imaging, CEA is developing a digital twin capable of modeling the entire infrared (IR) measurement chain, from the thermal source to the sensor.
The objective of this thesis is to create a thermal model that can predict heat fluxes and surface temperatures across the entire machine wall, with a goal of real-time computation. This approach is based on two key developments:
1)Development of a Monte Carlo statistical method: This method will solve the heat equation over large geometries in a complex environment, including a variety of heat sources and materials.
2)Acceleration of calculations on graphics processing units (GPU): Utilization of the Kokkos environment to optimize calculation performance while ensuring portability across all high-performance computing (HPC) platforms.
These developments will be validated and quantitatively evaluated on two experimental platforms: the laboratory test bench MAGRYT and the WEST tokamak, used as a demonstrator machine. The thesis will be conducted in a collaborative framework between CEA/DRF/IRFM and CEA/DES/ISAS. The developments will be integrated into the IR digital twin developed by CEA/IRFM for fusion machines and within a dedicated ray-tracing application for CEA/DES.

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