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Thesis
Home   /   Thesis   /   GREEN PHOTOCATALYTIC PRODUCTION OF FUEL-LIKE HYDROCARBONS USING FATTY ACID PHOTODECARBOXYLASE

GREEN PHOTOCATALYTIC PRODUCTION OF FUEL-LIKE HYDROCARBONS USING FATTY ACID PHOTODECARBOXYLASE

Biochemistry Life Sciences Molecular biophysics

Abstract

A PhD position in bio-photocatalysis at the I2BC/Paris-Saclay University & BIAM/Aix Marseille University in France is available for a dynamic and enthusiastic candidate. Funded by the French National Research Agency (ANR), the interdisciplinary project focuses on developing innovative biocatalysts for photo-production of hydrocarbon fuels of non-fossil origin.
The PhD project, entitled 'Green photocatalytic production of fuel-like hydrocarbons using Fatty Acid Photodecarboxylase,' aims to optimize the natural Fatty Acid Photodecarboxylase (FAP) enzyme for higher photostability and more efficient binding and photodecarboxylation of short fatty acid substrates, yielding liquid hydrocarbons.
Key responsibilities include preparing wild-type and mutant FAP proteins, conducting screening and tests of photoenzymatic activity, participating in enzyme evolution, characterizing new mutants using spectroscopic techniques, contributing to data analysis, writing scientific publications, and presenting results at conferences.
Requirements for applicants include a Master’s or engineering degree in relevant fields, practical laboratory skills, ability to work independently, proficiency in English and/or French, and readiness to relocate from Provence to Ile-de-France during the PhD.
The position offers the opportunity to contribute to sustainable energy research while gaining expertise in molecular biology, biochemistry, and optical spectroscopy. The PhD will be conducted within a collaborative ANR project involving four teams with diverse expertise and skills. The ideal candidate should integrate seamlessly into a multidisciplinary environment.
Supervisor will be Pavel Müller (pavel.muller@i2bc.paris-saclay.fr) and co-supervisor will be Damien Sorigué (damien.sorigue@cea.fr).Workplaces include the Institute of Biosciences and Biotechnologies of Aix-Marseille and CEA Saclay/Institut de Biologie Intégrative dela Cellule.
The contract begins between October 2024 and February 2025 and lasts for three years, with a monthly salary of 2400 € (brut). Applicants passionate about addressing energy challenges are encouraged to apply!

Laboratory

Institut des sciences du vivant Frédéric JOLIOT
SB2SM - Service de Bioénergétique, Biologie Stucturale, et Mécanismes
Laboratoire mécanismes fondamentaux de la bioénergétique
Paris-Saclay
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