



In the process of developing procedures, their miniaturization represents a major challenge for upstream research and development (R&D). Indeed, the miniaturization of procedures offers numerous advantages in terms of reducing the volume of raw materials, waste management, screening possibilities, automation, and safety for personnel.
To date, the counter-current liquid-liquid extraction process does not have a convincing miniaturization solution, although the applications are numerous: in pharmacy, chemical synthesis, nuclear, or nuclear medicine.
The CEA-ISEC in Marcoule has developed new microfluidic tools to perform these operations in a simple and operational manner, based on a fine understanding of the instabilities of two-phase flows in capillaries.
This 3-year study topic proposes:
- To experiment, understand, and finely model the flows and mass transfers;
- To optimize and then transpose the phenomena to industrially significant volumes;
- To publish and participate in international conferences.
The doctoral student will benefit from learning about the world of research in a team that values quality in the supervision and future of its doctoral students, in a multidisciplinary team ranging from process engineering to instrumentation, with projects ranging from research to industry.
General competencies in chemical engineering and mass transfer are required. Competencies in collaborating with our academic partners will be essential to the success of the study project.

