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Thesis
Home   /   Thesis   /   Optimization of gamma radiation detectors for medical imaging. Time-of-flight positron emission tomography

Optimization of gamma radiation detectors for medical imaging. Time-of-flight positron emission tomography

Corpuscular physics and outer space Life Sciences Medical imaging Particle physics

Abstract

Positron emission tomography (PET) is a nuclear medical imaging technique widely used in oncology and neurobiology.
We're proposing you to contribute to the development of an ambitious, patented technology: ClearMind. This gamma photon detector uses a monolithic PbWO4 crystal, in which Cherenkov and scintillation photons are produced. These optical photons are converted into electrons by a photoelectric layer and multiplied in a MicroChannel plate. The induced electrical signals are amplified by gigahertz amplifiers and digitized by SAMPIC fast acquisition modules. The opposite side of the crystal will be fitted with a matrix of silicon photomultiplier (SiPM).

You will work in an advanced instrumentation laboratory in a particle physics environment .
The first step will be to optimize the "components" of ClearMind detectors, in order to achieve nominal performance. We'll be working on scintillating crystals, optical interfaces, photoelectric layers and associated fast photodetectors, and readout electronics.
We will then characterize the performance of the prototype detectors on our measurement benches.
The data acquired will be interpreted using in-house analysis software written in C++ and/or Python.
Finally, we will compare the physical behavior of our detectors to Monté-Carlo simulation software (Geant4/Gate).
A particular effort will be devoted to the development of ultra-fast scintillating crystals in the context of a European collaboration.

Laboratory

Institut de recherche sur les lois fondamentales de l’univers
Service de Physique des Particules
Groupe Santé et Energie (GSE)
Paris-Saclay
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