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Thesis
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Lanthanide complexes acting as supramolecular glue to induce protein crystallization
BiochemistryLife SciencesStructural biology
Abstract
The primary objective of the project is to understand how dedicated lanthanide complexes induce protein crystallization and exploit them in new field of macromolecular crystallography. During the PhD project, we aim to (1) Explore the properties of the new molecules; (2) To develop a predictive tool on the propensity of the molecules to induce crystallization; (3) To develop the detection of sub-micron size crystals; (4) To study the possibility to generate crystals directly in cells.
Laboratory
Institut de Recherche Interdisciplinaire de Grenoble
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